I have not encountered many con-scripts encoding information in knots, rather than by marking flat media. I imagine that many conlangers would enjoy the inspiration of Andean khipus, which, going back to about 3,000 BCE, are ancient comparable with Proto-cuneiform.
Some useful resources include:
Various macrame websites and the concept 'sinnet' (you could decorate "nodes" within)
I think khipus and knot-writing most fascinating and I have greatly enjoyed the exercise. If people comment with specific curiosities, I will try to help. This question doesn't, per se, require an "answer" but I hope posting it may be useful and fruitful for the community.
Thanks, jk - Reinstate Monica, Andrew Ray, and curiousdannii for your input about correct posting!